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Organismal proteostasis: role of cell-nonautonomous regulation and transcellular chaperone signaling
Protein quality control is essential in all organisms and regulated by the proteostasis network (PN) and cell stress response pathways that maintain a functional proteome to promote cellular health. In this review, we describe how metazoans employ multiple modes of cell-nonautonomous signaling acros...
Autores principales: | van Oosten-Hawle, Patricija, Morimoto, Richard I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102760/ https://www.ncbi.nlm.nih.gov/pubmed/25030693 http://dx.doi.org/10.1101/gad.241125.114 |
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