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TRF2, but not TBP, mediates the transcription of ribosomal protein genes

The TCT core promoter element is present in most ribosomal protein (RP) genes in Drosophila and humans. Here we show that TBP (TATA box-binding protein)-related factor TRF2, but not TBP, is required for transcription of the TCT-dependent RP genes. In cells, TCT-dependent transcription, but not TATA-...

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Detalles Bibliográficos
Autores principales: Wang, Yuan-Liang, Duttke, Sascha H.C., Chen, Kai, Johnston, Jeff, Kassavetis, George A., Zeitlinger, Julia, Kadonaga, James T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102762/
https://www.ncbi.nlm.nih.gov/pubmed/24958592
http://dx.doi.org/10.1101/gad.245662.114