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A cell cycle-regulated Slx4–Dpb11 complex promotes the resolution of DNA repair intermediates linked to stalled replication

A key function of the cellular DNA damage response is to facilitate the bypass of replication fork-stalling DNA lesions. Template switch reactions allow such a bypass and involve the formation of DNA joint molecules (JMs) between sister chromatids. These JMs need to be resolved before cell division;...

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Detalles Bibliográficos
Autores principales: Gritenaite, Dalia, Princz, Lissa N., Szakal, Barnabas, Bantele, Susanne C.S., Wendeler, Lina, Schilbach, Sandra, Habermann, Bianca H., Matos, Joao, Lisby, Michael, Branzei, Dana, Pfander, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102767/
https://www.ncbi.nlm.nih.gov/pubmed/25030699
http://dx.doi.org/10.1101/gad.240515.114