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microRNAs 424 and 503 are mediators of the anti-proliferative and anti-invasive action of the thyroid hormone receptor beta

The thyroid hormone receptors (TRs) mediate tumor suppressive effects in hepatocarcinoma and breast cancer cells. Here we show that incubation of hepatocarcinoma SK-hep1 cells expressing TRb with the thyroid hormone T3 induces transcription of the polycistronic message coding for microRNAs 424 and 5...

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Detalles Bibliográficos
Autores principales: Ruiz-Llorente, Lidia, Ardila-González, Soraya, Fanjul, Luisa F, Martínez-Iglesias, Olaia, Aranda, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102780/
https://www.ncbi.nlm.nih.gov/pubmed/24796297