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Kinome profiling reveals breast cancer heterogeneity and identifies targeted therapeutic opportunities for triple negative breast cancer

Our understanding of breast cancer heterogeneity at the protein level is limited despite proteins being the ultimate effectors of cellular functions. We investigated the heterogeneity of breast cancer (41 primary tumors and 15 breast cancer cell lines) at the protein and phosphoprotein levels to ide...

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Detalles Bibliográficos
Autores principales: Al-Ejeh, Fares, Miranda, Mariska, Shi, Wei, Simpson, Peter T., Song, Sarah, Vargas, Ana Cristina, Saunus, Jodi M., Smart, Chanel E., Mariasegaram, Mythily, Wiegmans, Adrian P., Chenevix-Trench, Georgia, Lakhani, Sunil R., Khanna, Kum Kum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102798/
https://www.ncbi.nlm.nih.gov/pubmed/24762669