RAGE mediates S100A4-induced cell motility via MAPK/ERK and hypoxia signaling and is a prognostic biomarker for human colorectal cancer metastasis

Survival of colorectal cancer patients is strongly dependent on development of distant metastases. S100A4 is a prognostic biomarker and inducer for colorectal cancer metastasis. Besides exerting intracellular functions, S100A4 is secreted extracellularly. The receptor for advanced glycation end prod...

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Detalles Bibliográficos
Autores principales: Dahlmann, Mathias, Okhrimenko, Anna, Marcinkowski, Patrick, Osterland, Marc, Herrmann, Pia, Smith, Janice, Heizmann, Claus W., Schlag, Peter M., Stein, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102805/
https://www.ncbi.nlm.nih.gov/pubmed/24952599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102805/
https://www.ncbi.nlm.nih.gov/pubmed/24952599

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