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RAGE mediates S100A4-induced cell motility via MAPK/ERK and hypoxia signaling and is a prognostic biomarker for human colorectal cancer metastasis
Survival of colorectal cancer patients is strongly dependent on development of distant metastases. S100A4 is a prognostic biomarker and inducer for colorectal cancer metastasis. Besides exerting intracellular functions, S100A4 is secreted extracellularly. The receptor for advanced glycation end prod...
Autores principales: | Dahlmann, Mathias, Okhrimenko, Anna, Marcinkowski, Patrick, Osterland, Marc, Herrmann, Pia, Smith, Janice, Heizmann, Claus W., Schlag, Peter M., Stein, Ulrike |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102805/ https://www.ncbi.nlm.nih.gov/pubmed/24952599 |
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