HMGA1 silencing restores normal stem cell characteristics in colon cancer stem cells by increasing p53 levels

High-mobility group A1 (HMGA1) proteins are architectural chromatinic proteins, abundantly expressed during embryogenesis and in most cancer tissues, but expressed at low levels or absent in normal adult tissues. Several studies have demonstrated that HMGA1 proteins play a causal role in neoplastic...

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Detalles Bibliográficos
Autores principales: Puca, Francesca, Colamaio, Marianna, Federico, Antonella, Gemei, Marica, Tosti, Nadia, Bastos, André Uchimura, Vecchio, Luigi Del, Pece, Salvatore, Battista, Sabrina, Fusco, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102806/
https://www.ncbi.nlm.nih.gov/pubmed/24833610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102806/
https://www.ncbi.nlm.nih.gov/pubmed/24833610

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