Expression level of hTERT is regulated by somatic mutation and common single nucleotide polymorphism at promoter region in glioblastoma

We investigated the role of somatic mutations and a common single nucleotide polymorphism (SNP) in the hTERT promoter region on hTERT expression and clinical outcomes. The hTERT promoter region was sequenced from 48 glioblastomas. hTERT expression was analyzed by quantitative real time-PCR. The asso...

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Detalles Bibliográficos
Autores principales: Park, Chul-Kee, Lee, Se-Hoon, Kim, Ji Young, Kim, Ja Eun, Kim, Tae Min, Lee, Soon-Tae, Choi, Seung Hong, Park, Sung-Hye, Kim, Il Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102818/
https://www.ncbi.nlm.nih.gov/pubmed/24930669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102818/
https://www.ncbi.nlm.nih.gov/pubmed/24930669

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