KPT-330 has antitumour activity against non-small cell lung cancer

BACKGROUND: We investigated the biologic and pharmacologic activities of a chromosome region maintenance 1 (CRM1) inhibitor against human non-small cell lung cancer (NSCLC) cells both in vitro and in vivo. METHODS: The in vitro and in vivo effects of a novel CRM1 inhibitor (KPT-330) for a large numb...

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Detalles Bibliográficos
Autores principales: Sun, H, Hattori, N, Chien, W, Sun, Q, Sudo, M, E-Ling, G L, Ding, L, Lim, S L, Shacham, S, Kauffman, M, Nakamaki, T, Koeffler, H P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102938/
https://www.ncbi.nlm.nih.gov/pubmed/24946002
http://dx.doi.org/10.1038/bjc.2014.260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102938/
https://www.ncbi.nlm.nih.gov/pubmed/24946002
http://dx.doi.org/10.1038/bjc.2014.260

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