Structural dynamic analysis of apo and ATP-bound IRAK4 kinase

Interleukin-1 receptor-associated kinases (IRAKs) are Ser/Thr protein kinases that play an important role as signaling mediators in the signal transduction facilitated by the Toll-like receptor (TLR) and interleukin-1 receptor families. Among IRAK family members, IRAK4 is one of the drug targets for...

Descripción completa

Detalles Bibliográficos
Autores principales: Gosu, Vijayakumar, Choi, Sangdun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103033/
https://www.ncbi.nlm.nih.gov/pubmed/25034608
http://dx.doi.org/10.1038/srep05748

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103033/
https://www.ncbi.nlm.nih.gov/pubmed/25034608
http://dx.doi.org/10.1038/srep05748

Ejemplares similares