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Structural dynamic analysis of apo and ATP-bound IRAK4 kinase

Interleukin-1 receptor-associated kinases (IRAKs) are Ser/Thr protein kinases that play an important role as signaling mediators in the signal transduction facilitated by the Toll-like receptor (TLR) and interleukin-1 receptor families. Among IRAK family members, IRAK4 is one of the drug targets for...

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Detalles Bibliográficos
Autores principales:	Gosu, Vijayakumar, Choi, Sangdun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103033/ https://www.ncbi.nlm.nih.gov/pubmed/25034608 http://dx.doi.org/10.1038/srep05748

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