NSs protein of Schmallenberg virus counteracts the antiviral response of the cell by inhibiting its transcriptional machinery

Bunyaviruses have evolved a variety of strategies to counteract the antiviral defence systems of mammalian cells. Here we show that the NSs protein of Schmallenberg virus (SBV) induces the degradation of the RPB1 subunit of RNA polymerase II and consequently inhibits global cellular protein synthesi...

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Detalles Bibliográficos
Autores principales: Barry, Gerald, Varela, Mariana, Ratinier, Maxime, Blomström, Anne-Lie, Caporale, Marco, Seehusen, Frauke, Hahn, Kerstin, Schnettler, Esther, Baumgärtner, Wolfgang, Kohl, Alain, Palmarini, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for General Microbiology 2014
Materias:
Animal
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103064/
https://www.ncbi.nlm.nih.gov/pubmed/24828331
http://dx.doi.org/10.1099/vir.0.065425-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103064/
https://www.ncbi.nlm.nih.gov/pubmed/24828331
http://dx.doi.org/10.1099/vir.0.065425-0

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