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A complete, multi-level conformational clustering of antibody complementarity-determining regions

Classification of antibody complementarity-determining region (CDR) conformations is an important step that drives antibody modelling and engineering, prediction from sequence, directed mutagenesis and induced-fit studies, and allows inferences on sequence-to-structure relations. Most of the previou...

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Detalles Bibliográficos
Autores principales: Nikoloudis, Dimitris, Pitts, Jim E., Saldanha, José W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103072/
https://www.ncbi.nlm.nih.gov/pubmed/25071986
http://dx.doi.org/10.7717/peerj.456