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A complete, multi-level conformational clustering of antibody complementarity-determining regions
Classification of antibody complementarity-determining region (CDR) conformations is an important step that drives antibody modelling and engineering, prediction from sequence, directed mutagenesis and induced-fit studies, and allows inferences on sequence-to-structure relations. Most of the previou...
Autores principales: | Nikoloudis, Dimitris, Pitts, Jim E., Saldanha, José W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103072/ https://www.ncbi.nlm.nih.gov/pubmed/25071986 http://dx.doi.org/10.7717/peerj.456 |
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