Disjoint combinations profiling (DCP): a new method for the prediction of antibody CDR conformation from sequence

The accurate prediction of the conformation of Complementarity-Determining Regions (CDRs) is important in modelling antibodies for protein engineering applications. Specifically, the Canonical paradigm has proved successful in predicting the CDR conformation in antibody variable regions. It relies o...

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Detalles Bibliográficos
Autores principales: Nikoloudis, Dimitris, Pitts, Jim E., Saldanha, José W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2014
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103075/
https://www.ncbi.nlm.nih.gov/pubmed/25071985
http://dx.doi.org/10.7717/peerj.455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103075/
https://www.ncbi.nlm.nih.gov/pubmed/25071985
http://dx.doi.org/10.7717/peerj.455

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