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Disjoint combinations profiling (DCP): a new method for the prediction of antibody CDR conformation from sequence
The accurate prediction of the conformation of Complementarity-Determining Regions (CDRs) is important in modelling antibodies for protein engineering applications. Specifically, the Canonical paradigm has proved successful in predicting the CDR conformation in antibody variable regions. It relies o...
Autores principales: | Nikoloudis, Dimitris, Pitts, Jim E., Saldanha, José W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103075/ https://www.ncbi.nlm.nih.gov/pubmed/25071985 http://dx.doi.org/10.7717/peerj.455 |
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