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Characterization of the Caenorhabditis elegans HIM-6/BLM Helicase: Unwinding Recombination Intermediates

Mutations in three human RecQ genes are implicated in heritable human syndromes. Mutations in BLM, a RecQ gene, cause Bloom syndrome (BS), which is characterized by short stature, cancer predisposition, and sensitivity to sunlight. BLM is a RecQ DNA helicase that, with interacting proteins, is able...

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Detalles Bibliográficos
Autores principales: Jung, Hana, Lee, Jin A, Choi, Seoyoon, Lee, Hyunwoo, Ahn, Byungchan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103807/
https://www.ncbi.nlm.nih.gov/pubmed/25036527
http://dx.doi.org/10.1371/journal.pone.0102402