Combined Vildagliptin and Metformin Exert Better Cardioprotection than Monotherapy against Ischemia-Reperfusion Injury in Obese-Insulin Resistant Rats

BACKGROUND: Obese-insulin resistance caused by long-term high-fat diet (HFD) consumption is associated with left ventricular (LV) dysfunction and increased risk of myocardial infarction. Metformin and vildagliptin have been shown to exert cardioprotective effects. However, the effect of these drugs...

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Detalles Bibliográficos
Autores principales: Apaijai, Nattayaporn, Chinda, Kroekkiat, Palee, Siripong, Chattipakorn, Siriporn, Chattipakorn, Nipon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103813/
https://www.ncbi.nlm.nih.gov/pubmed/25036861
http://dx.doi.org/10.1371/journal.pone.0102374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103813/
https://www.ncbi.nlm.nih.gov/pubmed/25036861
http://dx.doi.org/10.1371/journal.pone.0102374

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