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Surfactant Protein D Inhibits HIV-1 Infection of Target Cells via Interference with gp120-CD4 Interaction and Modulates Pro-Inflammatory Cytokine Production

Surfactant Protein SP-D, a member of the collectin family, is a pattern recognition protein, secreted by mucosal epithelial cells and has an important role in innate immunity against various pathogens. In this study, we confirm that native human SP-D and a recombinant fragment of human SP-D (rhSP-D)...

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Detalles Bibliográficos
Autores principales: Pandit, Hrishikesh, Gopal, Sandhya, Sonawani, Archana, Yadav, Ajit Kumar, Qaseem, Asif S., Warke, Himangi, Patil, Anushree, Gajbhiye, Rahul, Kulkarni, Vijay, Al-Mozaini, Maha Ahmed, Idicula-Thomas, Susan, Kishore, Uday, Madan, Taruna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103819/
https://www.ncbi.nlm.nih.gov/pubmed/25036364
http://dx.doi.org/10.1371/journal.pone.0102395