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ERBB4 Promoter Polymorphism Is Associated with Poor Distant Disease-Free Survival in High-Risk Early Breast Cancer

A number of genetic variants have been linked to increased risk of breast cancer. Little is, however, known about the prognostic significance of hereditary factors. Here, we investigated the frequency and prognostic significance of two ERBB4 promoter region variants, −782G>T (rs62626348) and −815...

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Detalles Bibliográficos
Autores principales: Kurppa, Kari J., Rokavec, Matjaz, Sundvall, Maria, Kellokumpu-Lehtinen, Pirkko-Liisa, Joensuu, Heikki, Brauch, Hiltrud, Elenius, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103820/
https://www.ncbi.nlm.nih.gov/pubmed/25036186
http://dx.doi.org/10.1371/journal.pone.0102388