Computational Investigation of Locked Nucleic Acid (LNA) Nucleotides in the Active Sites of DNA Polymerases by Molecular Docking Simulations

Aptamers constitute a potential class of therapeutic molecules typically selected from a large pool of oligonucleotides against a specific target. With a scope of developing unique shorter aptamers with very high biostability and affinity, locked nucleic acid (LNA) nucleotides have been investigated...

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Detalles Bibliográficos
Autores principales: Poongavanam, Vasanthanathan, Madala, Praveen K., Højland, Torben, Veedu, Rakesh N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103837/
https://www.ncbi.nlm.nih.gov/pubmed/25036012
http://dx.doi.org/10.1371/journal.pone.0102126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103837/
https://www.ncbi.nlm.nih.gov/pubmed/25036012
http://dx.doi.org/10.1371/journal.pone.0102126

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