Hair Cell Regeneration after ATOH1 Gene Therapy in the Cochlea of Profoundly Deaf Adult Guinea Pigs

The degeneration of hair cells in the mammalian cochlea results in permanent sensorineural hearing loss. This study aimed to promote the regeneration of sensory hair cells in the mature cochlea and their reconnection with auditory neurons through the introduction of ATOH1, a transcription factor kno...

Descripción completa

Detalles Bibliográficos
Autores principales: Atkinson, Patrick J., Wise, Andrew K., Flynn, Brianna O., Nayagam, Bryony A., Richardson, Rachael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103851/
https://www.ncbi.nlm.nih.gov/pubmed/25036727
http://dx.doi.org/10.1371/journal.pone.0102077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103851/
https://www.ncbi.nlm.nih.gov/pubmed/25036727
http://dx.doi.org/10.1371/journal.pone.0102077

Ejemplares similares