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Hair Cell Regeneration after ATOH1 Gene Therapy in the Cochlea of Profoundly Deaf Adult Guinea Pigs
The degeneration of hair cells in the mammalian cochlea results in permanent sensorineural hearing loss. This study aimed to promote the regeneration of sensory hair cells in the mature cochlea and their reconnection with auditory neurons through the introduction of ATOH1, a transcription factor kno...
Autores principales: | Atkinson, Patrick J., Wise, Andrew K., Flynn, Brianna O., Nayagam, Bryony A., Richardson, Rachael T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103851/ https://www.ncbi.nlm.nih.gov/pubmed/25036727 http://dx.doi.org/10.1371/journal.pone.0102077 |
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