Diabetic Osteopenia by Decreased β-Catenin Signaling Is Partly Induced by Epigenetic Derepression of sFRP-4 Gene

In diabetics, methylglyoxal (MG), a glucose-derived metabolite, plays a noxious role by inducing oxidative stress, which causes and exacerbates a series of complications including low-turnover osteoporosis. In the present study, while MG treatment of mouse bone marrow stroma-derived ST2 cells rapidl...

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Detalles Bibliográficos
Autores principales: Mori, Kiyoshi, Kitazawa, Riko, Kondo, Takeshi, Mori, Michiko, Hamada, Yasuhiro, Nishida, Michiru, Minami, Yasuhiro, Haraguchi, Ryuma, Takahashi, Yutaka, Kitazawa, Sohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103869/
https://www.ncbi.nlm.nih.gov/pubmed/25036934
http://dx.doi.org/10.1371/journal.pone.0102797

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103869/
https://www.ncbi.nlm.nih.gov/pubmed/25036934
http://dx.doi.org/10.1371/journal.pone.0102797

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