Sumoylation of Human Argonaute 2 at Lysine-402 Regulates Its Stability

Gene silencing by small RNAs has emerged as a powerful post-transcriptional regulator of gene expression, however processes underlying regulation of the small RNA pathway in vivo are still largely elusive. Here, we identified sumoylation as a novel post-translational modification acting on Ago2, the...

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Detalles Bibliográficos
Autores principales: Sahin, Umut, Lapaquette, Pierre, Andrieux, Alexandra, Faure, Guilhem, Dejean, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103873/
https://www.ncbi.nlm.nih.gov/pubmed/25036361
http://dx.doi.org/10.1371/journal.pone.0102957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103873/
https://www.ncbi.nlm.nih.gov/pubmed/25036361
http://dx.doi.org/10.1371/journal.pone.0102957

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