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Sumoylation of Human Argonaute 2 at Lysine-402 Regulates Its Stability
Gene silencing by small RNAs has emerged as a powerful post-transcriptional regulator of gene expression, however processes underlying regulation of the small RNA pathway in vivo are still largely elusive. Here, we identified sumoylation as a novel post-translational modification acting on Ago2, the...
Autores principales: | Sahin, Umut, Lapaquette, Pierre, Andrieux, Alexandra, Faure, Guilhem, Dejean, Anne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103873/ https://www.ncbi.nlm.nih.gov/pubmed/25036361 http://dx.doi.org/10.1371/journal.pone.0102957 |
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