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Visualization of Transient Protein-Protein Interactions that Promote or Inhibit Amyloid Assembly

In the early stages of amyloid formation, heterogeneous populations of oligomeric species are generated, the affinity, specificity, and nature of which may promote, inhibit, or define the course of assembly. Despite the importance of the intermolecular interactions that initiate amyloid assembly, ou...

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Detalles Bibliográficos
Autores principales: Karamanos, Theodoros K., Kalverda, Arnout P., Thompson, Gary S., Radford, Sheena E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104025/
https://www.ncbi.nlm.nih.gov/pubmed/24981172
http://dx.doi.org/10.1016/j.molcel.2014.05.026