Cytosolic Quality Control of Mislocalized Proteins Requires RNF126 Recruitment to Bag6

Approximately 30% of eukaryotic proteins contain hydrophobic signals for localization to the secretory pathway. These proteins can be mislocalized in the cytosol due to mutations in their targeting signals, certain stresses, or intrinsic inefficiencies in their translocation. Mislocalized proteins (...

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Detalles Bibliográficos
Autores principales: Rodrigo-Brenni, Monica C., Gutierrez, Erik, Hegde, Ramanujan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104027/
https://www.ncbi.nlm.nih.gov/pubmed/24981174
http://dx.doi.org/10.1016/j.molcel.2014.05.025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104027/
https://www.ncbi.nlm.nih.gov/pubmed/24981174
http://dx.doi.org/10.1016/j.molcel.2014.05.025

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