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Cytosolic Quality Control of Mislocalized Proteins Requires RNF126 Recruitment to Bag6
Approximately 30% of eukaryotic proteins contain hydrophobic signals for localization to the secretory pathway. These proteins can be mislocalized in the cytosol due to mutations in their targeting signals, certain stresses, or intrinsic inefficiencies in their translocation. Mislocalized proteins (...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cell Press
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104027/ https://www.ncbi.nlm.nih.gov/pubmed/24981174 http://dx.doi.org/10.1016/j.molcel.2014.05.025 |