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The role of mRNA splicing in prostate cancer

Alternative splicing (AS) is a crucial step in gene expression. It is subject to intricate regulation, and its deregulation in cancer can lead to a wide array of neoplastic phenotypes. A large body of evidence implicates splice isoforms in most if not all hallmarks of cancer, including growth, apopt...

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Detalles Bibliográficos
Autores principales: Lapuk, Anna V, Volik, Stanislav V, Wang, Yuzhuo, Collins, Colin C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104073/
https://www.ncbi.nlm.nih.gov/pubmed/24830689
http://dx.doi.org/10.4103/1008-682X.127825