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Expression of Matrix Metalloproteinase-1 in Alveolar Macrophages, Type II Pneumocytes, and Airways in Smokers: Relationship to Lung Function and Emphysema

BACKGROUND: An imbalance between proteolytic enzymes and their inhibitors is thought to be involved in the pathogenesis of chronic obstructive pulmonary disease. Matrix metalloproteinase-1, also known as interstitial collagenase, has been implicated as a potentially important proteinase in the genes...

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Detalles Bibliográficos
Autores principales: Wallace, Alison M., Loy, Leanna B., Abboud, Raja T., D’Armiento, Jeanine M., Coxson, Harvey O., Muller, Nestor L., Kalloger, Steve, Li, Xing, Mark Elliott, W., English, John C., Finley, Richard J., Paré, Peter D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104162/
https://www.ncbi.nlm.nih.gov/pubmed/24792232
http://dx.doi.org/10.1007/s00408-014-9585-6