Reducing Pervasive False-Positive Identical-by-Descent Segments Detected by Large-Scale Pedigree Analysis

Analysis of genomic segments shared identical-by-descent (IBD) between individuals is fundamental to many genetic applications, from demographic inference to estimating the heritability of diseases, but IBD detection accuracy in nonsimulated data is largely unknown. In principle, it can be evaluated...

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Detalles Bibliográficos
Autores principales: Durand, Eric Y., Eriksson, Nicholas, McLean, Cory Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104314/
https://www.ncbi.nlm.nih.gov/pubmed/24784137
http://dx.doi.org/10.1093/molbev/msu151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104314/
https://www.ncbi.nlm.nih.gov/pubmed/24784137
http://dx.doi.org/10.1093/molbev/msu151

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