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A Molecular Profile of Cocaine Abuse Includes the Differential Expression of Genes that Regulate Transcription, Chromatin, and Dopamine Cell Phenotype

Chronic drug abuse, craving, and relapse are thought to be linked to long-lasting changes in neural gene expression arising through transcriptional and chromatin-related mechanisms. The key contributions of midbrain dopamine (DA)-synthesizing neurons throughout the addiction process provide a compel...

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Detalles Bibliográficos
Autores principales: Bannon, Michael J, Johnson, Magen M, Michelhaugh, Sharon K, Hartley, Zachary J, Halter, Steven D, David, James A, Kapatos, Gregory, Schmidt, Carl J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104338/
https://www.ncbi.nlm.nih.gov/pubmed/24642598
http://dx.doi.org/10.1038/npp.2014.70