Engineering light-inducible nuclear localization signals for precise spatiotemporal control of protein dynamics in living cells

The function of many eukaryotic proteins is regulated by highly dynamic changes in their nucleocytoplasmic distribution. The ability to precisely and reversibly control nuclear translocation would, therefore, allow dissecting and engineering cellular networks. Here we develop a genetically encoded,...

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Detalles Bibliográficos
Autores principales: Niopek, Dominik, Benzinger, Dirk, Roensch, Julia, Draebing, Thomas, Wehler, Pierre, Eils, Roland, Di Ventura, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104460/
https://www.ncbi.nlm.nih.gov/pubmed/25019686
http://dx.doi.org/10.1038/ncomms5404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104460/
https://www.ncbi.nlm.nih.gov/pubmed/25019686
http://dx.doi.org/10.1038/ncomms5404

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