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Engineering light-inducible nuclear localization signals for precise spatiotemporal control of protein dynamics in living cells
The function of many eukaryotic proteins is regulated by highly dynamic changes in their nucleocytoplasmic distribution. The ability to precisely and reversibly control nuclear translocation would, therefore, allow dissecting and engineering cellular networks. Here we develop a genetically encoded,...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Pub. Group
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104460/ https://www.ncbi.nlm.nih.gov/pubmed/25019686 http://dx.doi.org/10.1038/ncomms5404 |