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Accurate in silico identification of species-specific acetylation sites by integrating protein sequence-derived and functional features

Lysine acetylation is a reversible post-translational modification, playing an important role in cytokine signaling, transcriptional regulation, and apoptosis. To fully understand acetylation mechanisms, identification of substrates and specific acetylation sites is crucial. Experimental identificat...

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Detalles Bibliográficos
Autores principales: Li, Yuan, Wang, Mingjun, Wang, Huilin, Tan, Hao, Zhang, Ziding, Webb, Geoffrey I., Song, Jiangning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104576/
https://www.ncbi.nlm.nih.gov/pubmed/25042424
http://dx.doi.org/10.1038/srep05765