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Chitosan Hydrogel as siRNA vector for prolonged gene silencing

BACKGROUND: The periodontitis is one of the most prevalent diseases with alveolar resorption in adult people and is the main cause of the tooth loss. To investigate the possibility for protecting the loss of alveolar bone in periodontal diseases, a RNAi-based therapeutic strategy is applied for sile...

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Detalles Bibliográficos
Autores principales: Ma, Zhiwei, Yang, Chuanxu, Song, Wen, Wang, Qintao, Kjems, Jørgen, Gao, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104730/
https://www.ncbi.nlm.nih.gov/pubmed/24946934
http://dx.doi.org/10.1186/1477-3155-12-23