Cargando…

Chitosan Hydrogel as siRNA vector for prolonged gene silencing

BACKGROUND: The periodontitis is one of the most prevalent diseases with alveolar resorption in adult people and is the main cause of the tooth loss. To investigate the possibility for protecting the loss of alveolar bone in periodontal diseases, a RNAi-based therapeutic strategy is applied for sile...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ma, Zhiwei, Yang, Chuanxu, Song, Wen, Wang, Qintao, Kjems, Jørgen, Gao, Shan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104730/ https://www.ncbi.nlm.nih.gov/pubmed/24946934 http://dx.doi.org/10.1186/1477-3155-12-23

Ejemplares similares

Chitosan/siRNA functionalized titanium surface via a layer-by-layer approach for in vitro sustained gene silencing and osteogenic promotion
por: Song, Wen, et al.
Publicado: (2015)

Megalin-Mediated Specific Uptake of Chitosan/siRNA Nanoparticles in Mouse Kidney Proximal Tubule Epithelial Cells Enables AQP1 Gene Silencing
por: Gao, Shan, et al.
Publicado: (2014)

Chitosan/siRNA Nanoparticles Targeting Cyclooxygenase Type 2 Attenuate Unilateral Ureteral Obstruction-induced Kidney Injury in Mice
por: Yang, Chuanxu, et al.
Publicado: (2015)

Protection and Systemic Translocation of siRNA Following Oral Administration of Chitosan/siRNA Nanoparticles
por: Ballarín-González, Borja, et al.
Publicado: (2013)

Designing siRNA/chitosan-methacrylate complex nanolipogel for prolonged gene silencing effects
por: Cao, Ye, et al.
Publicado: (2022)

Optimized siRNA-PEG Conjugates for Extended Blood Circulation and Reduced Urine Excretion in Mice
por: Iversen, Frank, et al.
Publicado: (2013)

Covalently tethering siRNA to hydrogels for localized, controlled release and gene silencing
por: Nguyen, Minh Khanh, et al.
Publicado: (2019)

Calcium-siRNA Nanocomplexes Optimized by Bovine Serum Albumin Coating Can Achieve Convenient and Efficient siRNA Delivery for Periodontitis Therapy
por: Wang, Yang, et al.
Publicado: (2020)

Potential application of injectable chitosan hydrogel treated with siRNA in chronic rhinosinusitis therapy
por: CAO, CHENG, et al.
Publicado: (2015)

Layer by Layer Assembled Chitosan-Coated Gold Nanoparticles for Enhanced siRNA Delivery and Silencing
por: Shaabani, Elnaz, et al.
Publicado: (2021)

Therapeutic siRNA silencing in inflammatory monocytes
por: Leuschner, Florian, et al.
Publicado: (2011)

Prolonged efficiency of siRNA-mediated gene silencing in primary cultures of human preadipocytes and adipocytes
por: Lee, Mi-Jeong, et al.
Publicado: (2013)

Nanocarriers for delivery of siRNA as gene silencing mediator
por: Morales-Becerril, Aideé, et al.
Publicado: (2022)

siRNA Versus miRNA as Therapeutics for Gene Silencing
por: Lam, Jenny K W, et al.
Publicado: (2015)

Chitosan and Its Structural Modifications for siRNA Delivery
por: Al-Absi, Mona Y., et al.
Publicado: (2023)

Development and validation of vectors containing multiple siRNA expression cassettes for maximizing the efficiency of gene silencing
por: Wang, Shunqing, et al.
Publicado: (2006)

siRNA-Mediated Silencing of doublesex during Female Development of the Dengue Vector Mosquito Aedes aegypti
por: Mysore, Keshava, et al.
Publicado: (2015)

Effects of PEG anchors in PEGylated siRNA lipoplexes on in vitro gene-silencing effects and siRNA biodistribution in mice
por: Hattori, Yoshiyuki, et al.
Publicado: (2020)

In vivo silencing of alpha-synuclein using naked siRNA
por: Lewis, Jada, et al.
Publicado: (2008)

High potency silencing by single-stranded boranophosphate siRNA
por: Hall, Allison H. S., et al.
Publicado: (2006)

Strategies for Improving siRNA-Induced Gene Silencing Efficiency
por: Safari, Fatemeh, et al.
Publicado: (2017)

Identification of Novel Fibrosis Modifiers by In Vivo siRNA Silencing
por: Vollmann, Elisabeth H., et al.
Publicado: (2017)

In vivo therapeutic efficacy of TNFα silencing by folate-PEG-chitosan-DEAE/siRNA nanoparticles in arthritic mice
por: Shi, Qin, et al.
Publicado: (2018)

RORC2 Gene Silencing in Human Th17 Cells by siRNA: Design and Evaluation of Highly Efficient siRNA
por: Hakemi, Mazdak Ganjalikhani, et al.
Publicado: (2013)

Pathways of cellular internalisation of liposomes delivered siRNA and effects on siRNA engagement with target mRNA and silencing in cancer cells
por: Alshehri, Abdullah, et al.
Publicado: (2018)

Silencing of Her2, CCNB1 and PKC Genes by siRNA Results in Prolonged Retardation of Neuroblastoma Cell Division
por: Akimov, I.A., et al.
Publicado: (2011)

Injectable self-healing hydrogel with siRNA delivery property for sustained STING silencing and enhanced therapy of intervertebral disc degeneration
por: Chen, Jiaxin, et al.
Publicado: (2021)

Local siRNA delivery by non-viral vectors
por: Beilvert, F., et al.
Publicado: (2012)

The Role of the Arabidopsis Exosome in siRNA–Independent Silencing of Heterochromatic Loci
por: Shin, Jun-Hye, et al.
Publicado: (2013)

Dendrimers as Carriers for siRNA Delivery and Gene Silencing: A Review
por: Wu, Jiangyu, et al.
Publicado: (2013)

SiRNA silencing efficacy prediction based on a deep architecture
por: Han, Ye, et al.
Publicado: (2018)

Nuclear-targeted siRNA delivery for long-term gene silencing
por: Li, Na, et al.
Publicado: (2017)

siRNA Design to Silence the 3′UTR Region of Zika Virus
por: Perez-Mendez, María, et al.
Publicado: (2020)

Chitosan-modified poly(d,l-lactide-co-glycolide) nanospheres for improving siRNA delivery and gene-silencing effects
por: Tahara, Kohei, et al.
Publicado: (2010)

A Comparison of Target Gene Silencing using Synthetically Modified siRNA and shRNA That Express Recombinant Lentiviral Vectors
por: Spirin, P.V., et al.
Publicado: (2009)

Selection and Incorporation of siRNA Carrying Non-Viral Vector for Sustained Delivery from Gellan Gum Hydrogels
por: Nalbadis, Anastasios, et al.
Publicado: (2021)

Novel Ellipsoid Chitosan-Phthalate Lecithin Nanoparticles for siRNA Delivery
por: Saeed, Ramzi Mukred, et al.
Publicado: (2021)

Publisher Correction: Pathways of cellular internalisation of liposomes delivered siRNA and effects on siRNA engagement with target mRNA and silencing in cancer cells
por: Alshehri, Abdullah, et al.
Publicado: (2018)

Disulfide-Based Poly(amido amine)s for siRNA Delivery: Effects of Structure on siRNA Complexation, Cellular Uptake, Gene Silencing and Toxicity
por: Vader, Pieter, et al.
Publicado: (2010)

Chitosanase-based method for RNA isolation from cells transfected with chitosan/siRNA nanocomplexes for real-time RT-PCR in gene silencing
por: Alameh, Mohamad, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_hr2qdsukvoa90a9ru892f9carv