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HOXA10 is associated with temozolomide resistance through regulation of the homologous recombinant DNA repair pathway in glioblastoma cell lines

Temozolomide resistance is associated with multiple DNA repair pathways. We investigated homeobox (HOX) genes for their role in temozolomide resistance, focusing on the homologous recombination (HR) pathway, and we tested their therapeutic implications in conjunction with O(6)-methylguanine DNA meth...

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Detalles Bibliográficos
Autores principales: Kim, Jin Wook, Kim, Ji Young, Kim, Ja Eun, Kim, Seung-Ki, Chung, Hyun-Tai, Park, Chul-Kee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104759/
https://www.ncbi.nlm.nih.gov/pubmed/25061500