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Identification of a novel lytic peptide for the treatment of solid tumours

Originally known as host defence peptides for their substantial bacteriotoxic effects, many cationic antimicrobial peptides also exhibit a potent cytotoxic activity against cancer cells. Their mode of action is characterized mostly by electrostatic interactions with the plasma membrane, leading to m...

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Detalles Bibliográficos
Autores principales: Szczepanski, Claudia, Tenstad, Olav, Baumann, Anne, Martinez, Aurora, Myklebust, Reidar, Bjerkvig, Rolf, Prestegarden, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104761/
https://www.ncbi.nlm.nih.gov/pubmed/25061502