Mirk kinase inhibition targets ovarian cancer ascites

The Mirk/dyrk1B gene is commonly amplified or upregulated in ovarian cancers, and Mirk is an active kinase in these cancers. Mirk mediates cancer cell survival by decreasing toxic ROS levels through maintaining expression of a series of antioxidant genes, possibly through its transcriptional activat...

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Detalles Bibliográficos
Autores principales: Deng, Xiaobing, Hu, Jing, Cunningham, Mary J., Friedman, Eileen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104763/
https://www.ncbi.nlm.nih.gov/pubmed/25061503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104763/
https://www.ncbi.nlm.nih.gov/pubmed/25061503

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