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Systematic analysis of transcription-level effects of neurodegenerative diseases on human brain metabolism by a newly reconstructed brain-specific metabolic network

Network-oriented analysis is essential to identify those parts of a cell affected by a given perturbation. The effect of neurodegenerative perturbations in the form of diseases of brain metabolism was investigated by using a newly reconstructed brain-specific metabolic network. The developed stoichi...

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Detalles Bibliográficos
Autores principales: Sertbaş, Mustafa, Ülgen, Kutlu, Çakır, Tunahan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104795/
https://www.ncbi.nlm.nih.gov/pubmed/25061554
http://dx.doi.org/10.1016/j.fob.2014.05.006