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IDENTIFICATION OF ERYTHROFERRONE AS AN ERYTHROID REGULATOR OF IRON METABOLISM

Recovery from blood loss requires a greatly enhanced supply of iron to support expanded erythropoiesis. After hemorrhage, suppression of the iron-regulatory hormone hepcidin allows increased iron absorption and mobilization from stores. We identified a new hormone, erythroferrone (ERFE), which media...

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Detalles Bibliográficos
Autores principales: Kautz, Léon, Jung, Grace, Valore, Erika V., Rivella, Stefano, Nemeth, Elizabeta, Ganz, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104984/
https://www.ncbi.nlm.nih.gov/pubmed/24880340
http://dx.doi.org/10.1038/ng.2996