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APPLICATION OF 6-NITROCOUMARIN AS A SUBSTRATE FOR THE FLUORESCENT DETECTION OF NITROREDUCTASE ACTIVITY IN Sporothrix schenckii

INTRODUCTION: Sporothrix schenckii is a thermal dimorphic pathogenic fungus causing a subcutaneous mycosis, sporotrichosis. Nitrocoumarin represents a fluorogenic substrate class where the microbial nitroreductase activity produces several derivatives, already used in several other enzyme assays. Th...

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Detalles Bibliográficos
Autores principales: Stopiglia, Cheila Denise Ottonelli, Carissimi, Mariana, Daboit, Tatiane Caroline, Stefani, Valter, Corbellini, Valeriano Antonio, Scroferneker, Maria Lúcia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto de Medicina Tropical 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105074/
https://www.ncbi.nlm.nih.gov/pubmed/24037291
http://dx.doi.org/10.1590/S0036-46652013000500010