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SPE-8, a protein-tyrosine kinase, localizes to the spermatid cell membrane through interaction with other members of the SPE-8 group spermatid activation signaling pathway in C. elegans

BACKGROUND: The SPE-8 group gene products transduce the signal for spermatid activation initiated by extracellular zinc in C. elegans. Mutations in the spe-8 group genes result in hermaphrodite-derived spermatids that cannot activate to crawling spermatozoa, although spermatids from mutant males act...

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Detalles Bibliográficos
Autores principales: Muhlrad, Paul J, Clark, Jessica N, Nasri, Ubaydah, Sullivan, Nicholas G, LaMunyon, Craig W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105102/
https://www.ncbi.nlm.nih.gov/pubmed/25022984
http://dx.doi.org/10.1186/1471-2156-15-83