XBP1 Promotes Triple Negative Breast Cancer By Controlling the HIF1 α Pathway

Cancer cells induce a set of adaptive response pathways to survive in the face of stressors due to inadequate vascularization(1). One such adaptive pathway is the unfolded protein (UPR) or endoplasmic reticulum (ER) stress response mediated in part by the ER-localized transmembrane sensor IRE1(2) an...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Xi, Iliopoulos, Dimitrios, Zhang, Qing, Tang, Qianzi, Greenblatt, Matthew B., Hatziapostolou, Maria, Lim, Elgene, Tam, Wai Leong, Ni, Min, Chen, Yiwen, Mai, Junhua, Shen, Haifa, Hu, Dorothy Z., Adoro, Stanley, Hu, Bella, Song, Minkyung, Tan, Chen, Landis, Melissa D., Ferrari, Mauro, Shin, Sandra J., Brown, Myles, Chang, Jenny C., Liu, X. Shirley, Glimcher, Laurie H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105133/
https://www.ncbi.nlm.nih.gov/pubmed/24670641
http://dx.doi.org/10.1038/nature13119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105133/
https://www.ncbi.nlm.nih.gov/pubmed/24670641
http://dx.doi.org/10.1038/nature13119

Ejemplares similares