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A Convergent Synthetic Platform for Single-Nanoparticle Combination Cancer Therapy: Ratiometric Loading and Controlled Release of Cisplatin, Doxorubicin, and Camptothecin

[Image: see text] The synthesis of polymer therapeutics capable of controlled loading and synchronized release of multiple therapeutic agents remains a formidable challenge in drug delivery and synthetic polymer chemistry. Herein, we report the synthesis of polymer nanoparticles (NPs) that carry pre...

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Detalles Bibliográficos
Autores principales: Liao, Longyan, Liu, Jenny, Dreaden, Erik C., Morton, Stephen W., Shopsowitz, Kevin E., Hammond, Paula T., Johnson, Jeremiah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105175/
https://www.ncbi.nlm.nih.gov/pubmed/24724706
http://dx.doi.org/10.1021/ja502011g