Hydrophobicity and Helicity Regulate the Antifungal Activity of 14-Helical β-Peptides

[Image: see text] Candida albicans is one of the most prevalent fungal pathogens, causing both mucosal candidiasis and invasive candidemia. Antimicrobial peptides (AMPs), part of the human innate immune system, have been shown to exhibit antifungal activity but have not been effective as pharmaceuti...

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Detalles Bibliográficos
Autores principales: Lee, Myung-Ryul, Raman, Namrata, Gellman, Samuel H., Lynn, David M., Palecek, Sean P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105187/
https://www.ncbi.nlm.nih.gov/pubmed/24837702
http://dx.doi.org/10.1021/cb500203e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105187/
https://www.ncbi.nlm.nih.gov/pubmed/24837702
http://dx.doi.org/10.1021/cb500203e

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