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Hydrophobicity and Helicity Regulate the Antifungal Activity of 14-Helical β-Peptides
[Image: see text] Candida albicans is one of the most prevalent fungal pathogens, causing both mucosal candidiasis and invasive candidemia. Antimicrobial peptides (AMPs), part of the human innate immune system, have been shown to exhibit antifungal activity but have not been effective as pharmaceuti...
Autores principales: | Lee, Myung-Ryul, Raman, Namrata, Gellman, Samuel H., Lynn, David M., Palecek, Sean P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105187/ https://www.ncbi.nlm.nih.gov/pubmed/24837702 http://dx.doi.org/10.1021/cb500203e |
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